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The Lipid metabolism plays a fundamental role in regulating cholesterol and triglyceride levels, which are key factors in cardiovascular health and overall well-being. Our Lipid Metabolism Genetic Test analyses specific genes associated with fat metabolism, helping you understand your body’s ability to process different lipids and its predisposition to conditions such as hypercholesterolemia, dyslipidaemia, and cardiovascular disease..

By examining genetic variations in key lipid-related genes, this test provides essential insights into your unique metabolic profile, enabling you to make informed decisions about your diet, lifestyle, and medical interventions if necessary.

This genetic test analyses four critical genes involved in lipid metabolism:

• APOA1 (Apolipoprotein A1): Plays a vital role in reverse cholesterol transport and is a major component of HDL (“good” cholesterol). Variants in this gene can influence HDL levels and cardiovascular risk.
• APOC3 (Apolipoprotein C3): Regulates triglyceride metabolism, impacting the likelihood of hypertriglyceridemia and related metabolic disorders.
• CETP (Cholesteryl Ester Transfer Protein): Controls the transfer of cholesterol between lipoproteins. Certain variants can lower HDL cholesterol and raise LDL cholesterol, increasing cardiovascular risk.
• LDLR (Low-Density Lipoprotein Receptor): Responsible for removing LDL (“bad” cholesterol) from the blood. Mutations in this gene can contribute to familial hypercholesterolemia and atherosclerosis.

Through this test, you will gain personalized insights into your genetic predisposition for lipid metabolism and cardiovascular health. This data can help guide dietary choices, exercise routines, and potential medical treatments to optimize heart health.
For an example of the report, please click here:

Genetic variations in APOA1, APOC3, CETP, and LDLR can significantly impact how your body metabolizes fats. The presence of unfavourable variants may lead to:

• Low HDL cholesterol levels, reducing your body’s ability to remove excess cholesterol.
• Elevated triglyceride levels, increasing the risk of metabolic syndrome and heart disease.
• Higher LDL cholesterol levels, leading to a greater risk of atherosclerosis and other cardiovascular complications.
• Familial hypercholesterolemia, an inherited condition that raises cholesterol levels from an early age.

By identifying these genetic predispositions, individuals can take proactive steps to manage cardiovascular risks through targeted lifestyle adjustments, dietary modifications, and, if necessary, medical intervention

A Lipid Metabolism DNA test does not require you to provide a blood sample. Our test is performed using buccal swabs that we provide in our home sample collection kit. Collecting samples is quick and easy if you follow the instructions provided carefully.

Sample collection instructions can be found on our “How to Collect DNA Samples” page.

Please read our terms and conditions for clinical and health-related testing carefully and make sure you understand them before placing an order.

Please contact us with any questions or to place an order.

We also offer tests to determine your predisposition to disease, coeliac disease, lactose intolerance and your lipid metabolism. For more information, please click here.

If you’re interested in how your genes impact more than just caffeine metabolism, you might want to explore our Sport DNA Test, which can reveal your ideal sport and even provide a personalized training plan based on your genetic profile.

Disclaimer: Test results are for informational and/or educational purposes only and should NOT be used to make medical, health or other decisions without consulting a physician. Always talk to your physician and seek professional help before taking action. This test is not a substitute for a visit to a physician, or the advice or services of a physician or other qualified healthcare professional.

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