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Salt consumption plays a key role in regulating blood pressure and supporting cardiovascular health. However, not everyone reacts to sodium in the same way. Some individuals are more sensitive to it, which can increase the risk of hypertension and other related conditions. Our Salt Sensitivity DNA Test helps you discover how your body processes sodium and its impact on your blood pressure.

This genetic test focuses on specific genetic variants, like those in the ACE gene, that affect blood pressure regulation and sodium metabolism. By understanding these genetic factors, you can take control of your diet and overall health, making personalized decisions that suit your unique genetic profile.

The DNA Test provides valuable insights into:

• Salt Sensitivity Status: The test analyses genetic markers, such as the I/D (Insertion/Deletion) polymorphism in the ACE gene, to assess your body’s ability to process sodium. Based on your results, you’ll learn if you have high, moderate, or low salt sensitivity:
  • High Salt Sensitivity: You may need to significantly reduce sodium intake to avoid raising blood pressure.
  • Moderate Salt Sensitivity: Excess sodium over time may increase your risk of hypertension.
  • Low Salt Sensitivity: Your body processes sodium more efficiently, but maintaining a balanced diet is still important.
• Blood Pressure Regulation: Gain insights into how your body manages sodium and blood pressure, helping assess your risk for hypertension and cardiovascular issues for more informed health decisions.
• Personalized Recommendations: The test provides tailored advice on diet, exercise, and lifestyle changes to manage blood pressure and reduce the risk of long-term cardiovascular problems. The results are displayed in an easy-to-read summary table with color-coded interpretations for clarity.

The report includes peer-reviewed scientific references to ensure the accuracy and reliability of your results.

• Informed Dietary Choices: Understanding your genetic salt sensitivity allows you to adjust your diet accordingly. For example, those with high sensitivity can reduce sodium intake and increase potassium-rich foods to maintain balance.
• Reduced Health Risks: Identifying your genetic predisposition helps you mitigate the risk of hypertension and cardiovascular diseases through personalized lifestyle changes.
• Optimized Health Management: Receive actionable tips for diet, exercise, and stress management to support healthy blood pressure and overall well-being.

The ACE (Angiotensin-Converting Enzyme) gene plays a crucial role in the regulation of blood pressure and sodium metabolism. The ACE gene encodes an enzyme that is involved in the renin-angiotensin system, which helps control blood pressure and fluid balance. Variations in this gene can affect ACE enzyme levels, which can influence your susceptibility to hypertension and sodium retention.

• ACE Gene Variants: The most common variant analysed is the I/D (Insertion/Deletion) polymorphism, where:
• D (Deletion) Variant is linked to higher ACE levels, which can increase the risk of hypertension and sodium retention.
• I (Insertion) Variant is associated with lower ACE levels, which may have a protective effect on blood pressure.

By analysing this gene, the test gives you a clear picture of your salt sensitivity and the likelihood of developing hypertension due to your genetic makeup.

A Salt Sensitivity DNA test does not require you to provide a blood sample. Our test is performed using buccal swabs that we provide in our home sample collection kit. Collecting samples is quick and easy if you follow the instructions provided carefully.

Sample collection instructions can be found on our “How to Collect DNA Samples” page.

Please read our terms and conditions for clinical and health-related testing carefully and make sure you understand them before placing an order.

Please contact us with any questions or to place an order.

We also offer tests to determine your predisposition to disease, coeliac disease, lactose intolerance and your lipid metabolism. For more information, please click here.

If you’re interested in how your genes impact more than just caffeine metabolism, you might want to explore our Sport DNA Test, which can reveal your ideal sport and even provide a personalized training plan based on your genetic profile.

Disclaimer: Test results are for informational and/or educational purposes only and should NOT be used to make medical, health or other decisions without consulting a physician. Always talk to your physician and seek professional help before taking action. This test is not a substitute for a visit to a physician, or the advice or services of a physician or other qualified healthcare professional.

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